{
    "url": "https://mhesi.nrct.go.th/archives/s/mhesi_archives/item/6424",
    "o:resource_class": "dctype:Text",
    "dcterms:title": [
        "Determination of Antibiotic Substances from Actinomycetes Strain ST-13-2 and Antibacterial Activity"
    ],
    "dcterms:creator": [
        "Somyot Laorpaksa\nAurapin Yingyong\nSanti Thoongsuwan\nAreerat Pongsopida"
    ],
    "dcterms:subject": [
        "Actinomyces\nAntibiotics"
    ],
    "dcterms:description": [
        "This article presents a study on the antibiotic-producing capability of Actinomycetes strain ST-13-2, utilizing the bioautograph technique to assess antibacterial activity. The findings revealed that the produced compounds are water-soluble basic antibiotics with a clear inhibitory effect against Staphylococcus aureus. Some of the substances exhibited more than one inhibition zone, and one of the zones had an Rf value equivalent to that of Cloxacillin (Rf = 0.26), indicating potential antimicrobial properties.\n\nFurther testing demonstrated that the antibiotic substances from this strain were capable of inhibiting the growth of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae, based on 30 clinical isolates obtained from hospitalized patients. The results showed that all bacterial strains were inhibited, except for Pseudomonas aeruginosa, which exhibited only partial susceptibility."
    ],
    "dcterms:publisher": [
        "National Research Council Thailand"
    ],
    "dcterms:date": [
        "1988"
    ],
    "dcterms:type": [
        "Text"
    ],
    "dcterms:format": [
        "pdf"
    ],
    "dcterms:source": [
        "Journal of National Research Council, Vol. 20, No. 1 January-June 1988, 1-20"
    ],
    "dcterms:language": [
        "en"
    ],
    "dcterms:coverage": [
        "สื่อและเอกสารเผยแพร่"
    ],
    "dcterms:rights": [
        "This is an open access document. You are free to Share and Use under the terms of the Creative commons license."
    ],
    "dcterms:alternative": [
        "การบ่งชี้สารปฏิชีวนะที่ผลิตโดยเชื้อแอคติโนมัยซีตีส สายพันธุ์ ST-13-2 และฤทธิ์ในการต้านแบคทีเรีย"
    ],
    "dcterms:created": [
        "2025-05-31"
    ],
    "dcterms:isVersionOf": [
        "6427"
    ],
    "dcterms:accessRights": [
        "This document is distributed under the terms of the Creative Commons Attribution 4.0 International (CC-BY-NC-ND 4.0) and copyright of the Chulachomklao Royal Military Academy"
    ],
    "dcterms:license": [
        "This document is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License."
    ],
    "dcterms:rightsHolder": [
        "Ministry of Higher Education, Science, Research and Innovation"
    ]
},