Url
	https://mhesi.nrct.go.th/archives/s/mhesi_archives/item/6424
Resource class
	dctype:Text
Title
	Determination of Antibiotic Substances from Actinomycetes Strain ST-13-2 and Antibacterial Activity
Creator
	Somyot Laorpaksa
Aurapin Yingyong
Santi Thoongsuwan
Areerat Pongsopida
Subject
	Actinomyces
Antibiotics
Description
	This article presents a study on the antibiotic-producing capability of Actinomycetes strain ST-13-2, utilizing the bioautograph technique to assess antibacterial activity. The findings revealed that the produced compounds are water-soluble basic antibiotics with a clear inhibitory effect against Staphylococcus aureus. Some of the substances exhibited more than one inhibition zone, and one of the zones had an Rf value equivalent to that of Cloxacillin (Rf = 0.26), indicating potential antimicrobial properties.

Further testing demonstrated that the antibiotic substances from this strain were capable of inhibiting the growth of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae, based on 30 clinical isolates obtained from hospitalized patients. The results showed that all bacterial strains were inhibited, except for Pseudomonas aeruginosa, which exhibited only partial susceptibility.
Publisher
	National Research Council Thailand
Date
	1988
Type
	Text
Format
	pdf
Source
	Journal of National Research Council, Vol. 20, No. 1 January-June 1988, 1-20
Language
	en
Coverage
	สื่อและเอกสารเผยแพร่
Rights
	This is an open access document. You are free to Share and Use under the terms of the Creative commons license.
Alternative Title
	การบ่งชี้สารปฏิชีวนะที่ผลิตโดยเชื้อแอคติโนมัยซีตีส สายพันธุ์ ST-13-2 และฤทธิ์ในการต้านแบคทีเรีย
Date Created
	2025-05-31
Is Version Of
	6427
Access Rights
	This document is distributed under the terms of the Creative Commons Attribution 4.0 International (CC-BY-NC-ND 4.0) and copyright of the Chulachomklao Royal Military Academy
License
	This document is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Rights Holder
	Ministry of Higher Education, Science, Research and Innovation

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