{
    "url": "https://mhesi.nrct.go.th/archives/s/mhesi_archives/item/6458",
    "o:resource_class": "dctype:Text",
    "dcterms:title": [
        "The Effect of Phytohormones and Some Additives on Tissue Culture Establishment and in vitro Production of Alkaloids from Arcangelisia FLAVA MERR"
    ],
    "dcterms:creator": [
        "Wandee Yanpaisan"
    ],
    "dcterms:subject": [
        "Plant tissue culture\nAlkaloids\nMedicinal plants\nPlant hormones"
    ],
    "dcterms:description": [
        "For the economical progressive of developing countries such as Thailand, drug is one of the essential basic factor that should be seriously considered and urged to manufacture locally. As a result it would reduce a commercial inbalance from importing drugs. This management would also prevent drug deficiency in critical periods. The berberine alkaloid is one of the potential drugs distributed in some genera of plants including Arcangelisia flava Merr., which is a Thai native medicinal plant found wildly grown in southeastern and southern parts of Thailand. It seems to contain a reliable high amount of berberine in its roots and stems. So A. flava may become an interesting source of berberine for modern drug production. However, the berberine mostly accumulates in A. flava roots and it takes approximately 5 years to produce a proper high alkaloid containing roots. Thus, the application of tissue culture techniques for culturing of A. flava in an artificial media was studied to shorten the period of growth and to increase the percentage of berberine by in vitro culture. In addion, this investigation would elucidate some basic knowledges of biosynthetic pathway of certain alkaloids in A. flava in culture condition."
    ],
    "dcterms:publisher": [
        "National Research Council Thailand"
    ],
    "dcterms:date": [
        "1989"
    ],
    "dcterms:type": [
        "Text"
    ],
    "dcterms:format": [
        "pdf"
    ],
    "dcterms:source": [
        "Journal of the National Research Council of Thailand Vol. 21 no. 1 January-June 1989, 1-28\nLibrary and Information Center, National Institute of Development Administration"
    ],
    "dcterms:language": [
        "en\nth"
    ],
    "dcterms:coverage": [
        "สื่อและเอกสารเผยแพร่"
    ],
    "dcterms:rights": [
        "This is an open access document. You are free to Share and Use under the terms of the Creative commons license."
    ],
    "dcterms:alternative": [
        "ผลของฮอร์โมนพืชและสารบางชนิดต่อการสร้างเนื้อเยื่อและการผลิตแอลคาลอยด์ของขมิ้นเครือในหลอดทดลอง"
    ],
    "dcterms:created": [
        "2025-05-31"
    ],
    "dcterms:extent": [
        "27 leaves"
    ],
    "dcterms:accessRights": [
        "This document is distributed under the terms of the Creative Commons Attribution 4.0 International (CC-BY-NC-ND 4.0) and copyright of the Chulachomklao Royal Military Academy"
    ],
    "dcterms:license": [
        "This document is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License."
    ],
    "dcterms:rightsHolder": [
        "Ministry of Higher Education, Science, Research and Innovation"
    ]
},